Medical assistant pay in Columbia, SC at a glance
Median salary
$40,680$19.56 per hour · $3,390 monthly · BLS May 2025Run the numbers on your own pay
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Medical assistant salary in Columbia, SC after taxes
Medical assistants pay range in Columbia, SC, hourly and yearly
BLS May 2025 estimates for the Columbia, SC metropolitan statistical area. Monthly and take-home figures are ours, computed from the annual wage.
| Percentile | Hourly | Monthly | Yearly | After tax a year (SC) |
|---|---|---|---|---|
| 10th percentile | $17.02/hr | $2,951 | $35,410 | $30,226 |
| 25th percentile | $17.93/hr | $3,108 | $37,290 | $31,699 |
| MedianMedian | $19.56/hr | $3,390 | $40,680 | $34,352 |
| 75th percentile | $22.00/hr | $3,814 | $45,770 | $38,237 |
| 90th percentile | $22.86/hr | $3,962 | $47,540 | $39,542 |
Is $40,680 a good salary in Columbia, SC?
It depends on what else people there earn and what things cost. Here is the median for medical assistants next to both.
Medical assistants pay in South Carolina and across the U.S.
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Medical assistant pay in Columbia, SC: common questions
What is the median salary for medical assistants in Columbia, SC?
The BLS median annual wage for medical assistants in the Columbia, SC metro area was $40,680 in May 2025, about $3,390 a month or $19.56 an hour. Statewide, the South Carolina median for this job is $41,160, so the metro pays 1% below the state.
What is the hourly pay for medical assistants in Columbia, SC?
The median hourly wage for medical assistants in Columbia, SC was $19.56 in the BLS survey. One in ten earned less than $17.02 an hour and one in ten earned more than $22.86.
How many medical assistants work in Columbia, SC?
BLS estimated 2,190 jobs for medical assistants in the metro in May 2025, or 5.6 of every 1,000 jobs. Its location quotient of 1.06 means the job is more concentrated here than in the country as a whole.
What is the pay range for medical assistants in Columbia, SC?
BLS wage estimates for medical assistants in Columbia, SC run from $35,410 at the 10th percentile to $37,290 at the 25th, $45,770 at the 75th, and $47,540 at the 90th. These are points in the wage distribution, not experience levels.
How much do medical assistants take home after taxes in Columbia, SC?
On a median gross salary of $40,680, an estimated $34,352 lands in net take-home pay per year ($1,321 biweekly) for a single filer claiming the standard deduction in South Carolina in 2026. Total tax withholding equals $6,328 (an effective rate of 15.6%).
How much do medical assistants make per month in Columbia, SC?
On the median annual salary of $40,680, gross monthly income is $3,390. After federal, FICA, and South Carolina state income taxes, estimated net take-home pay is $2,863 per month (or $1,321 every two weeks).
Is $40,680 a good salary in Columbia, SC?
At $40,680, the median salary for medical assistants is 59.5% of the Columbia, SC median household income ($68,359). It is 12% below the $46,430 median for all jobs in the metro. The BEA regional price parity is 93.7, so prices here run 6.3% below the U.S. average.