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Sioux Falls, SD-MN metro area · BLS May 2025 · Updated

How much does a medical assistant make in Sioux Falls, SD?

In the Sioux Falls, SD-MN metropolitan area, medical assistants earned a median of $43,760 a year ($21.04 an hour) in May 2025, according to the BLS Occupational Employment and Wage Statistics survey for the metro. BLS counted 620 of these jobs there. That is 9% below the $47,970 median for all jobs in the metro. The middle 80% earned between $36,700 and $49,540; these percentiles do not measure years of experience. Applying 2026 federal and Minnesota tax rules to the median leaves an estimated $35,819 in take-home pay.

Medical assistant pay in Sioux Falls, SD at a glance

Median salary

$43,760$21.04 per hour · $3,647 monthly · BLS May 2025
10th percentile$36,700$17.64/hr
25th percentile$38,380$18.45/hr
75th percentile$46,700$22.45/hr
90th percentile$49,540$23.82/hr
Jobs in this metro620Location quotient 0.66 (U.S. = 1.00)
Against all jobs here9% belowAll-jobs median $47,970
Against Minnesota13% belowStatewide median $50,480
Against the U.S.4% belowNational median $45,690

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Same U.S. tax tables as the rest of the site. Change the salary, state, or filing status.

Take-home payWhat $44,000 a year leaves after tax in MinnesotaFederal tax, FICA and Minnesota withholding on that salary, with the other 49 states beside it.
By the hour$21 an hour is how much a yearWeekly, biweekly and monthly gross at 2,080 hours, plus time and a half.
HousingWhat a $44,000 salary buys at today's ratesPrice range, down payment and the monthly payment behind it, on current mortgage rates.
Local pricesWhat $44,000 is worth where you liveRent, groceries and the local price level against the national average.
Same stateEvery occupation Minnesota publishes a wage forThe biggest employers, the best paid, and what is distinctive about Minnesota.

Medical assistant salary in Sioux Falls, SD after taxes

$43,760
$15,000$90,000
Filing status:
Gross salary breakdown$43,760
Net 82%
Fed 7%
MN 3%
FICA 8%
Annual take-home$35,819After all taxes
Monthly deposit$2,985Estimated per month
Biweekly paycheck$1,378Every 2 weeks (26/yr)
Effective tax rate18.2%Total tax burden
Federal income tax$3,071 / yr
Minnesota state income tax$1,523 / yr
FICA (Social Security & Medicare)$3,348 / yr
Customize deductions in full Minnesota calculator

Medical assistants pay range in Sioux Falls, SD, hourly and yearly

BLS May 2025 estimates for the Sioux Falls, SD-MN metropolitan statistical area. Monthly and take-home figures are ours, computed from the annual wage.

What medical assistants earned in the Sioux Falls, SD-MN metro area, May 2025
PercentileHourlyMonthlyYearlyAfter tax a year (MN)
10th percentile$17.64/hr$3,058$36,700$30,524
25th percentile$18.45/hr$3,198$38,380$31,784
MedianMedian$21.04/hr$3,647$43,760$35,819
75th percentile$22.45/hr$3,892$46,700$38,024
90th percentile$23.82/hr$4,128$49,540$40,140

Is $43,760 a good salary in Sioux Falls, SD?

It depends on what else people there earn and what things cost. Here is the median for medical assistants next to both.

Median household income$82,754Census Bureau ACS
Local price level (U.S. = 100)90.69.4% below national average
One paycheck vs. a household52.9%of area median income

The same job statewide and nationally, and a calculator for your own paycheck.

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Medical assistants pay in other Minnesota metros

Metros in the same state that are closest in size to Sioux Falls, SD. A statewide average can hide differences this large.

Medical assistant pay in Sioux Falls, SD: common questions

What is the median salary for medical assistants in Sioux Falls, SD-MN?

The BLS median annual wage for medical assistants in the Sioux Falls, SD-MN metro area was $43,760 in May 2025, about $3,647 a month or $21.04 an hour. Statewide, the Minnesota median for this job is $50,480, so the metro pays 13% below the state.

What is the hourly pay for medical assistants in Sioux Falls, SD-MN?

The median hourly wage for medical assistants in Sioux Falls, SD-MN was $21.04 in the BLS survey. One in ten earned less than $17.64 an hour and one in ten earned more than $23.82.

How many medical assistants work in Sioux Falls, SD-MN?

BLS estimated 620 jobs for medical assistants in the metro in May 2025, or 3.5 of every 1,000 jobs. Its location quotient of 0.66 means the job is less concentrated here than in the country as a whole.

What is the pay range for medical assistants in Sioux Falls, SD-MN?

BLS wage estimates for medical assistants in Sioux Falls, SD-MN run from $36,700 at the 10th percentile to $38,380 at the 25th, $46,700 at the 75th, and $49,540 at the 90th. These are points in the wage distribution, not experience levels.

How much do medical assistants take home after taxes in Sioux Falls, SD-MN?

On a median gross salary of $43,760, an estimated $35,819 lands in net take-home pay per year ($1,378 biweekly) for a single filer claiming the standard deduction in Minnesota in 2026. Total tax withholding equals $7,941 (an effective rate of 18.1%).

How much do medical assistants make per month in Sioux Falls, SD-MN?

On the median annual salary of $43,760, gross monthly income is $3,647. After federal, FICA, and Minnesota state income taxes, estimated net take-home pay is $2,985 per month (or $1,378 every two weeks).

Is $43,760 a good salary in Sioux Falls, SD-MN?

At $43,760, the median salary for medical assistants is 52.9% of the Sioux Falls, SD-MN median household income ($82,754). It is 9% below the $47,970 median for all jobs in the metro. The BEA regional price parity is 90.6, so prices here run 9.4% below the U.S. average.