St. Louis, MO-IL metro area · BLS May 2025 · Updated

How much does a medical assistant make in St. Louis, MO?

In the St. Louis, MO-IL metropolitan area, medical assistants earned a median of $44,710 a year ($21.50 an hour) in May 2025, according to the BLS Occupational Employment and Wage Statistics survey for the metro. BLS counted 6,170 of these jobs there. That is 11% below the $49,990 median for all jobs in the metro. The middle 80% earned between $36,670 and $48,620; these percentiles do not measure years of experience. Applying 2026 federal and Illinois tax rules to the median leaves an estimated $36,036 in take-home pay.

Medical assistant pay in St. Louis, MO at a glance

Median salary

$44,710$21.50 per hour · $3,726 monthly · BLS May 2025
10th percentile$36,670$17.63/hr
25th percentile$38,550$18.53/hr
75th percentile$47,600$22.88/hr
90th percentile$48,620$23.38/hr
Jobs in this metro6,170Location quotient 0.87 (U.S. = 1.00)
Against all jobs here11% belowAll-jobs median $49,990
Against Illinois3% belowStatewide median $46,090
Against the U.S.2% belowNational median $45,690

Run the numbers on your own pay

Same U.S. tax tables as the rest of the site. Change the salary, state, or filing status.

Medical assistant salary in St. Louis, MO after taxes

$44,710
$15,000$90,000
Filing status:
Gross salary breakdown$44,710
Net 81%
Fed 7%
IL 5%
FICA 8%
Annual take-home$36,036After all taxes
Monthly deposit$3,003Estimated per month
Biweekly paycheck$1,386Every 2 weeks (26/yr)
Effective tax rate19.4%Total tax burden
Federal income tax$3,185 / yr
Illinois state income tax$2,068 / yr
FICA (Social Security & Medicare)$3,420 / yr

Medical assistants pay range in St. Louis, MO, hourly and yearly

BLS May 2025 estimates for the St. Louis, MO-IL metropolitan statistical area. Monthly and take-home figures are ours, computed from the annual wage.

What medical assistants earned in the St. Louis, MO-IL metro area, May 2025
PercentileHourlyMonthlyYearlyAfter tax a year (IL)
10th percentile$17.63/hr$3,056$36,670$29,974
25th percentile$18.53/hr$3,213$38,550$31,391
MedianMedian$21.50/hr$3,726$44,710$36,036
75th percentile$22.88/hr$3,967$47,600$38,215
90th percentile$23.38/hr$4,052$48,620$38,984

Is $44,710 a good salary in St. Louis, MO?

It depends on what else people there earn and what things cost. Here is the median for medical assistants next to both.

Median household income$80,196Census Bureau ACS
Local price level (U.S. = 100)95.14.9% below national average
One paycheck vs. a household55.8%of area median income

The same job statewide and nationally, and a calculator for your own paycheck.

Medical assistant pay in St. Louis, MO: common questions

What is the median salary for medical assistants in St. Louis, MO-IL?

The BLS median annual wage for medical assistants in the St. Louis, MO-IL metro area was $44,710 in May 2025, about $3,726 a month or $21.50 an hour. Statewide, the Illinois median for this job is $46,090, so the metro pays 3% below the state.

What is the hourly pay for medical assistants in St. Louis, MO-IL?

The median hourly wage for medical assistants in St. Louis, MO-IL was $21.50 in the BLS survey. One in ten earned less than $17.63 an hour and one in ten earned more than $23.38.

How many medical assistants work in St. Louis, MO-IL?

BLS estimated 6,170 jobs for medical assistants in the metro in May 2025, or 4.6 of every 1,000 jobs. Its location quotient of 0.87 means the job is less concentrated here than in the country as a whole.

What is the pay range for medical assistants in St. Louis, MO-IL?

BLS wage estimates for medical assistants in St. Louis, MO-IL run from $36,670 at the 10th percentile to $38,550 at the 25th, $47,600 at the 75th, and $48,620 at the 90th. These are points in the wage distribution, not experience levels.

How much do medical assistants take home after taxes in St. Louis, MO-IL?

On a median gross salary of $44,710, an estimated $36,036 lands in net take-home pay per year ($1,386 biweekly) for a single filer claiming the standard deduction in Illinois in 2026. Total tax withholding equals $8,674 (an effective rate of 19.4%).

How much do medical assistants make per month in St. Louis, MO-IL?

On the median annual salary of $44,710, gross monthly income is $3,726. After federal, FICA, and Illinois state income taxes, estimated net take-home pay is $3,003 per month (or $1,386 every two weeks).

Is $44,710 a good salary in St. Louis, MO-IL?

At $44,710, the median salary for medical assistants is 55.8% of the St. Louis, MO-IL median household income ($80,196). It is 11% below the $49,990 median for all jobs in the metro. The BEA regional price parity is 95.1, so prices here run 4.9% below the U.S. average.