St. Louis, MO-IL metro area · BLS May 2025 · Updated

How much does a registered nurse make in St. Louis, MO?

In the St. Louis, MO-IL metropolitan area, registered nurses earned a median of $83,180 a year ($39.99 an hour) in May 2025, according to the BLS Occupational Employment and Wage Statistics survey for the metro. BLS counted 35,200 of these jobs there. That is 66% above the $49,990 median for all jobs in the metro. The middle 80% earned between $63,440 and $104,460; these percentiles do not measure years of experience. Applying 2026 federal and Illinois tax rules to the median leaves an estimated $63,375 in take-home pay.

Registered nurse pay in St. Louis, MO at a glance

Median salary

$83,180$39.99 per hour · $6,932 monthly · BLS May 2025
10th percentile$63,440$30.50/hr
25th percentile$77,410$37.22/hr
75th percentile$100,230$48.19/hr
90th percentile$104,460$50.22/hr
Jobs in this metro35,200Location quotient 1.21 (U.S. = 1.00)
Against all jobs here66% aboveAll-jobs median $49,990
Against Illinois13% belowStatewide median $95,990
Against the U.S.15% belowNational median $97,550

Run the numbers on your own pay

Same U.S. tax tables as the rest of the site. Change the salary, state, or filing status.

Registered nurse salary in St. Louis, MO after taxes

$83,180
$30,000$170,000
Filing status:
Gross salary breakdown$83,180
Net 76%
Fed 11%
IL 5%
FICA 8%
Annual take-home$63,375After all taxes
Monthly deposit$5,281Estimated per month
Biweekly paycheck$2,437Every 2 weeks (26/yr)
Effective tax rate23.8%Total tax burden
Federal income tax$9,470 / yr
Illinois state income tax$3,973 / yr
FICA (Social Security & Medicare)$6,363 / yr

Registered nurses pay range in St. Louis, MO, hourly and yearly

BLS May 2025 estimates for the St. Louis, MO-IL metropolitan statistical area. Monthly and take-home figures are ours, computed from the annual wage.

What registered nurses earned in the St. Louis, MO-IL metro area, May 2025
PercentileHourlyMonthlyYearlyAfter tax a year (IL)
10th percentile$30.50/hr$5,287$63,440$50,159
25th percentile$37.22/hr$6,451$77,410$59,601
MedianMedian$39.99/hr$6,932$83,180$63,375
75th percentile$48.19/hr$8,353$100,230$74,525
90th percentile$50.22/hr$8,705$104,460$77,292

Is $83,180 a good salary in St. Louis, MO?

It depends on what else people there earn and what things cost. Here is the median for registered nurses next to both.

Median household income$80,196Census Bureau ACS
Local price level (U.S. = 100)95.14.9% below national average
One paycheck vs. a household103.7%of area median income

The same job statewide and nationally, and a calculator for your own paycheck.

Registered nurse pay in St. Louis, MO: common questions

What is the median salary for registered nurses in St. Louis, MO-IL?

The BLS median annual wage for registered nurses in the St. Louis, MO-IL metro area was $83,180 in May 2025, about $6,932 a month or $39.99 an hour. Statewide, the Illinois median for this job is $95,990, so the metro pays 13% below the state.

What is the hourly pay for registered nurses in St. Louis, MO-IL?

The median hourly wage for registered nurses in St. Louis, MO-IL was $39.99 in the BLS survey. One in ten earned less than $30.50 an hour and one in ten earned more than $50.22.

How many registered nurses work in St. Louis, MO-IL?

BLS estimated 35,200 jobs for registered nurses in the metro in May 2025, or 26.2 of every 1,000 jobs. Its location quotient of 1.21 means the job is more concentrated here than in the country as a whole.

What is the pay range for registered nurses in St. Louis, MO-IL?

BLS wage estimates for registered nurses in St. Louis, MO-IL run from $63,440 at the 10th percentile to $77,410 at the 25th, $100,230 at the 75th, and $104,460 at the 90th. These are points in the wage distribution, not experience levels.

How much do registered nurses take home after taxes in St. Louis, MO-IL?

On a median gross salary of $83,180, an estimated $63,375 lands in net take-home pay per year ($2,437 biweekly) for a single filer claiming the standard deduction in Illinois in 2026. Total tax withholding equals $19,805 (an effective rate of 23.8%).

How much do registered nurses make per month in St. Louis, MO-IL?

On the median annual salary of $83,180, gross monthly income is $6,932. After federal, FICA, and Illinois state income taxes, estimated net take-home pay is $5,281 per month (or $2,437 every two weeks).

Is $83,180 a good salary in St. Louis, MO-IL?

At $83,180, the median salary for registered nurses is 103.7% of the St. Louis, MO-IL median household income ($80,196). It is 66% above the $49,990 median for all jobs in the metro. The BEA regional price parity is 95.1, so prices here run 4.9% below the U.S. average.